Description
Cytokeratin 7 is an intermediate filament protein (IFP) of 54 kDa that recognizes the simple epithelium found in most glandular and transitional epithelia; but not that which is found in the stratified squamous epithelia. This rabbit monoclonal antibody [clone BC1] is highly specific to cytokeratin 7 and shows no cross-reaction with other IFP’s. Cytokeratin 7 is expressed in epithelial cells of ovary, lung and breast. It is often used in conjunction with cytokeratin 20 and CDX-2 in distinguishing pulmonary, ovarian and breast carcinomas (CK7+) from most colon carcinomas (CK7-).
SPECIFICATIONS
Specifications
| WEIGHT | N/A |
|---|---|
| DIMENSIONS | N/A |
| INTENDED USE | IVD |
| SPECIES REACTIVITY | Human |
| SOURCE | Rabbit Monoclonal |
| CLONE | BC1, Biocare Clone |
| ISOTYPE | IgG |
| ANTIGEN | CK7 |
| LOCALIZATION | Cytoplasmic |
| POSITIVE CONTROL | Breast, lung or ovarian cancers |
DATASHEETS & SDS
REFERENCES
1. Qi W, et al. Appl Immunohistochem Mol Morphol. 2009 May; 17(3):233-8.
2. Ross DS, et al. Am J Clin Pathol. 2013 Jan; 139(1):62-70.
3. McCluggage WG, Young RH. Semin Diagn Pathol. 2005 Feb; 22(1):3-32.
4. Sousa V, et al. Virchows Arch. 2011 May; 458(5):571-81.
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