Description
Human CD10 antibody, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with TdT+ lymphoblastic leukemia, follicular germinal cell lymphoma, Burkitt’s lymphoma and chronic myelocytic leukemia. CD10 also marks normal early lymphoid progenitor cells, immature B-cells in adult bone marrow and germinal cells in normal tonsil and normal lymphoid tissue. It is also expressed in some non-lymphoid tissues such as fibroblasts, breast myoepithelium and brush border of kidney. CD10 antibody may be used in a panel for mantle cell lymphoma with Cyclin D1 (+), CD43 (+), CD5 (+), IgM (+), CD23 (-) and CD10 (-).
SPECIFICATIONS
Specifications
| INTENDED USE | IVD |
|---|---|
| SPECIES REACTIVITY | Human |
| SOURCE | Mouse Monoclonal |
| CLONE | 56C6 |
| ISOTYPE | IgG1 |
| ANTIGEN | CD10 |
| LOCALIZATION | Cell Membrane |
| POSITIVE CONTROL | Tonsil or Kidney |
DATASHEETS & SDS
| Download Data Sheet |
| Download RUO Data Sheet |
| Download SDS Sheet |
Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.
REFERENCES
1. Kaufmann O, et al. Am J Clin Pathol. 1999 Jan; 111(1):117-22.
2. Kurtin PJ, et al. Am J Clin Pathol. 1999 Sep; 112(3):319-29.
3. de Leon ED, et al. Mod Pathol. 1998 Nov; 11(11):1046-51.
4. de Boer CJ, et al. Ann Oncol. 1997; 8 Suppl 2:109-17.
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