Description
This antibody cocktail recognizes a protein of 68-75 kDa, identified as Chromogranin A antibody. The combination of LK2H10 and PHE5 is specifically designed for sensitive detection of Chromogranin A in formalin-fixed, paraffin-embedded (FFPE) tissues. Chromogranin A is present in neuroendocrine cells throughout the body. It has been shown that Chromogranin A is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas and other neuroendocrine tumors. Chromogranin A may be a useful tumor marker to aid in predicting the extent of neuroendocrine differentiation and the time to recurrence in prostate cancer.
SPECIFICATIONS
Specifications
| WEIGHT | N/A |
|---|---|
| DIMENSIONS | N/A |
| INTENDED USE | IVD |
| SPECIES REACTIVITY | Human, Mouse, Rat |
| SOURCE | Mouse Monoclonal |
| CLONE | LK2H10 + PHE5 |
| ISOTYPE | IgG1 + IgG1 |
| ANTIGEN | Chromogranin A |
| LOCALIZATION | Finely granular cytoplasm |
| POSITIVE CONTROL | Pancreas or adrenal gland |
DATASHEETS & SDS
INTERNATIONAL
ONCORE PROTOCOL
| ANTIBODY | DOWNLOAD |
|---|---|
| Download Oncore Protocol |
REFERENCES
1. Kamiya N, et al. Int J Urol. 2008 May; 15(5):423-8.
2. Kokubo H, et al. Urology. 2005 Jul; 66(1):135-40.
3. Park SJ, et al. Appl Immunohistochem Mol Morphol. 2010 Jul; 18(4):348-52.
4. Conlon JM. Regul Pept. 2010 Nov; 165(1):5-11.
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