Description
CD163 is useful in identifying cells of monocyte/macrophage lineage in normal and neoplastic conditions (1,2). This antibody reacts with human scavenger receptor cysteine-rich protein CD163 (p155, M130) found on mononuclear phagocytes including human monocytes and macrophages (1). Compared with the CD68 antibodies, studies have shown that CD163 demonstrated greater specificity as a marker of disorders of monocyte/macrophage origin (2). However, immunohistochemical evaluation of CD163 expression does not seem to be a sensitive means of determining monocytic differentiation of AMLs or myeloid sarcoma (3).
SPECIFICATIONS
Specifications
| WEIGHT | N/A |
|---|---|
| DIMENSIONS | N/A |
| INTENDED USE | IVD |
| SPECIES REACTIVITY | Human |
| SOURCE | Mouse Monoclonal |
| CLONE | 10D6 |
| ISOTYPE | IgG1 |
| ANTIGEN | CD163 |
| LOCALIZATION | Membrane |
| POSITIVE CONTROL | Tonsil or Placenta |
DATASHEETS & SDS
| Download Data Sheet |
| Download RUO Data Sheet |
| Download SDS Sheet |
Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.
REFERENCES
1. Lee CH, et al. Clin Cancer Res. 2008 Mar 1; 14(5):1423-30.
2. Lau SK, Chu PG, Weiss LM. Am J Clin Pathol. 2004 Nov; 122(5):794-801.
3. Nguyen TT, et al. Am J Surg Pathol. 2005 May; 29(5):617-24.
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