Description
L26 + CD3 antibodies allow B-cell and T-cell lymphomas to be identified on the same slide. L26 (CD20) reacts with the majority of B-cells present in peripheral blood and lymphoid tissues. In normal lymphoid tissue, L26 marks B-cells in germinal centers, particularly immunoblasts and rarely marks T-cells. This antibody has been shown to be a reliable pan B-cell marker. The rabbit monoclonal CD3 reacts with the intracytoplasmic portion of the CD3 antigen expressed by T-cells. CD3 stains human T-cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues.
SPECIFICATIONS
Specifications
| WEIGHT | N/A |
|---|---|
| DIMENSIONS | N/A |
| INTENDED USE | IVD |
| SPECIES REACTIVITY | Human |
| SOURCE | Mouse Monoclonal, Rabbit Monoclonal |
| CLONE | L26 + SP7 |
| ISOTYPE | IgG2a + IgG |
| ANTIGEN | L26: B-cells , CD3: T-cells |
| LOCALIZATION | L26: cytoplasmic (red), CD3: cytoplasmic (brown) |
| POSITIVE CONTROL | Tonsil |
DATASHEETS & SDS
| Download DS Data Sheet |
| Download RUO Data Sheet for International |
| Download SDS Sheet |
Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.
REFERENCES
1. Nguyen DT, et al. Hematopathol Mol Hematol. 1996; 10(3):135-50.
2. Chadburn A, Knowles DM. Am J Clin Pathol. 1994 Sep; 102(3):284-91.
3. Davey FR, et al. Am J Pathol. 1987 Oct; 129(1):54-63.
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